Influenza a virus triggers acute exacerbation of chronic obstructive pulmonary disease by increasing proinflammatory cytokines secretion via NLRP3 inflammasome activation

Influenza a virus triggers acute exacerbation of chronic obstructive pulmonary disease by increasing proinflammatory cytokines secretion via NLRP3 inflammasome activation

Abstract Background Influenza A virus (IAV) triggers acute exacerbation of chronic obstructive pulmonary disease (AECOPD), but the molecular mechanisms remain unclear. In this study, we investigated the role of IAV induced NLRP3 inflammasome activation to increase airway inflammation response in the...

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Bibliographic Details
Main Authors: Shuang Ji, Meng-Yuan Dai, Yun Huang, Xiang-Chun Ren, Meng-Long Jiang, Jin-Ping Qiao, Wen-Ying Zhang, Yuan-Hong Xu, Ji-Long Shen, Ren-Quan Zhang, Guang-He Fei
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Inflammation
Subjects:
Airway inflammation
Acute exacerbation
Chronic obstructive pulmonary disease
Influenza A virus
MCC950
NLRP3 inflammasome pathway
Online Access:https://doi.org/10.1186/s12950-022-00305-y

Internet

https://doi.org/10.1186/s12950-022-00305-y

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