Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence

Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence

ABSTRACTSeasonal influenza, causes hundreds of thousands of deaths annually, posing a severe threat to human health. Currently available influenza vaccines are targeted only at specific strains or conserved epitopes; however, these vaccines are not completely efficacious because influenza viruses ca...

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Bibliographic Details
Main Authors: Ning Ma, Zhi-Wu Xia, Zhe-Gang Zhang, Xuan-Xuan Nian, Xue-Dan Li, Zheng Gong, Guo-Mei Zhang, Yang Le, Rong Zhou, Jia-You Zhang, Xiao-Ming Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
H1N1 influenza virus
hemagglutinin
mRNA vaccine
lipid nanoparticle
cross-protection
consensus sequence
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2202278

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https://www.tandfonline.com/doi/10.1080/22221751.2023.2202278

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