TRPV4 regulates migration and tube formation of human retinal capillary endothelial cells

Abstract Background Ca2+ entry plays an important role in modulating endothelial cell migration and tube formation. Transient receptor potential cation channel subfamily V member 4 (TRPV4) is a Ca2+-permeable channel that is widely expressed in endothelial cells. It has been reported that TRPV4 is e...

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Bibliographic Details
Main Authors: Lei Wen, Yue-Chun Wen, Gen-Jie Ke, Si-Qin Sun, Kai Dong, Lin Wang, Rong-Feng Liao
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-018-0697-2