Ena drives invasive macrophage migration in Drosophila embryos
SUMMARY It is seldom the primary tumour that proves fatal in cancer, with metastasis the fundamental pathological process for disease progression. Upregulation of Mena, a member of the evolutionarily conserved Ena/VASP family of actin cytoskeletal regulators, promotes metastasis and invasive motilit...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2011-01-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/4/1/126 |