Ena drives invasive macrophage migration in Drosophila embryos

SUMMARY It is seldom the primary tumour that proves fatal in cancer, with metastasis the fundamental pathological process for disease progression. Upregulation of Mena, a member of the evolutionarily conserved Ena/VASP family of actin cytoskeletal regulators, promotes metastasis and invasive motilit...

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Bibliographic Details
Main Authors: Philippa K. Tucker, Iwan R. Evans, Will Wood
Format: Article
Language:English
Published: The Company of Biologists 2011-01-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/1/126