Anti-CD73 antibody activates human B cells, enhances humoral responses and induces redistribution of B cells in patients with cancer

Background CD73 is widely expressed on immune cells playing a critical role in immunomodulatory functions including cell adhesion and migration, as a costimulatory molecule for T cells and in production of adenosine. The function of CD73 expressed on B cells has not been fully characterized. Mupadol...

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Detalhes bibliográficos
Principais autores: Thomas Marron, Brett G M Hughes, Jason John Luke, Shenshen Hu, Suresh Mahabhashyam, Richard A Miller, William B Jones, Jaime R Merchan, Stephen B Willingham
Formato: Artigo
Idioma:English
Publicado em: BMJ Publishing Group 2022-12-01
coleção:Journal for ImmunoTherapy of Cancer
Acesso em linha:https://jitc.bmj.com/content/10/12/e005802.full