Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity

Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity

Hepatic glucose production (HGP) is an important component of glucose homeostasis, and deregulated HGP, particularly through gluconeogenesis, contributes to hyperglycemia and pathology of type-2 diabetes (T2D). It has been shown that the gluconeogenic gene expression is governed primarily by the tra...

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Bibliographic Details
Main Authors: Aijun Qiao, Wenxia Ma, Ying Jiang, Chaoshan Han, Baolong Yan, Junlan Zhou, Gangjian Qin
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Sam68
hepatocytes
gluconeogenesis
high-fat diet
diabetes
CRTC2
Online Access:https://www.mdpi.com/1422-0067/23/19/11469

Internet

https://www.mdpi.com/1422-0067/23/19/11469

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