Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin

Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin

Abstract Osteosarcoma (OS) is the most common malignant bone tumor and a leading cause of cancer‐related deaths in children and adolescents. Current standard treatments for OS are a combination of preoperative chemotherapy, surgical resection, and adjuvant chemotherapy. Cisplatin is used as the stan...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Naohiro Oka, Akiyoshi Komuro, Hisayuki Amano, Suman Dash, Masahiko Honda, Kazushige Ota, Shunji Nishimura, Takeshi Ueda, Masao Akagi, Hitoshi Okada
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Wiley 2020-08-01
Ráidu:Pharmacology Research & Perspectives
Fáttát:
chemoresistance
metabolism
mitochondria
osteosarcoma
ROS
Liŋkkat:https://doi.org/10.1002/prp2.632

Interneahtta

https://doi.org/10.1002/prp2.632

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