Regeneration of T cells from human-induced pluripotent stem cells for CAR-T cell medicated immunotherapy

Regeneration of T cells from human-induced pluripotent stem cells for CAR-T cell medicated immunotherapy

Background: Chimeric antigen receptor (CAR) T cell treatment involves in vitro production of T cells from patient blood with synthetic receptors specific to a cancer antigen. They circumvent the major histocompatibility complex to recognize the tumor antigen, reducing hematologic malignancy remissio...

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Bibliographic Details
Main Authors: Yanyan Chen, Pufeng Huang, Mengda Niu, Chuanhuizi Tian, Tingting Zhang, Zhiping Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
immunotherapy
cell differentiation
human induced pluripotent stem cells
lymphomagenesis
hiPS-CAR-T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1159507/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2023.1159507/full

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