The Effect of Sera from Children with Obstructive Sleep Apnea Syndrome (OSAS) on Human Cardiomyocytes Differentiated from Human Embryonic Stem Cells

The Effect of Sera from Children with Obstructive Sleep Apnea Syndrome (OSAS) on Human Cardiomyocytes Differentiated from Human Embryonic Stem Cells

Obstructive sleep apnea syndrome (OSAS) patients suffer from cardiovascular morbidity, which is the leading cause of death in this disease. Based on our previous work with transformed cell lines and primary rat cardiomyocytes, we determined that upon incubation with sera from pediatric OSAS patients...

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Bibliographic Details
Main Authors: Hen Haddad, Sharon Etzion, Tatiana Rabinski, Rivka Ofir, Danielle Regev, Yoram Etzion, Jacob Gopas, Aviv Goldbart
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
obstructive sleep apnea
sera
inflammation
NF-κB
cardiomyocytes (CM) derived from human embryonic stem cells (hES)
intracellular [Ca<sup>2+</sup>]<sub>i</sub> signaling
Online Access:https://www.mdpi.com/1422-0067/22/21/11418

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https://www.mdpi.com/1422-0067/22/21/11418

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