A link between central kynurenine metabolism and bone strength in rats with chronic kidney disease

A link between central kynurenine metabolism and bone strength in rats with chronic kidney disease

Background Disturbances in mineral and bone metabolism represent one of the most complex complications of chronic kidney disease (CKD). Serotonin, a monoamine synthesized from tryptophan, may play a potential role in bone metabolism. Brain-derived serotonin exerts a positive effect on the bone struc...

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Bibliographic Details
Main Authors: Bartlomiej Kalaska, Krystyna Pawlak, Ewa Oksztulska-Kolanek, Tomasz Domaniewski, Beata Znorko, Malgorzata Karbowska, Aleksandra Citkowska, Joanna Rogalska, Alicja Roszczenko, Malgorzata M. Brzoska, Dariusz Pawlak
Format: Article
Language:English
Published: PeerJ Inc. 2017-04-01
Series:PeerJ
Subjects:
Bone disorders
Chronic kidney disease
Kynurenine pathway
Brain
Online Access:https://peerj.com/articles/3199.pdf

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https://peerj.com/articles/3199.pdf

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