Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in <italic toggle="yes">Bacteroides thetaiotaomicron</italic> Strains

Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in <italic toggle="yes">Bacteroides thetaiotaomicron</italic> Strains

ABSTRACT Genomic differences between gut-resident bacterial strains likely underlie significant interindividual variation in microbiome function. Traditional methods of determining community composition, such as 16S rRNA gene amplicon sequencing, fail to capture this functional diversity. Metagenomi...

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Bibliographic Details
Main Authors: Payal Joglekar, Erica D. Sonnenburg, Steven K. Higginbottom, Kristen A. Earle, Carl Morland, Sarah Shapiro-Ward, David N. Bolam, Justin L. Sonnenburg
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mSphere
Subjects:
Bacteroides
microbiome
polysaccharide utilization locus
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00185-18

Internet

https://journals.asm.org/doi/10.1128/mSphereDirect.00185-18

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