A Sensitive, Green, and Fast LC–MS/MS Analytical Method for the Quantification of Ribociclib: Evaluation of the Metabolic Stability in HLMs

Ribociclib (Kisqali<sup>®</sup>) is a pharmacological agent that has great selectivity as a cyclin-dependent kinase 4/6 inhibitor. It has received regulatory approval for its application in the treatment of breast cancer. The objective of the current study was to develop a rapid, green,...

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Bibliographic Details
Main Authors: Mohamed W. Attwa, Ali S. Abdelhameed, Adnan A. Kadi
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Separations
Subjects:
Online Access:https://www.mdpi.com/2297-8739/10/9/472