Novel Curcumin Inspired Bis-Chalcone Promotes Endoplasmic Reticulum Stress and Glioblastoma Neurosphere Cell Death

Novel Curcumin Inspired Bis-Chalcone Promotes Endoplasmic Reticulum Stress and Glioblastoma Neurosphere Cell Death

Glioblastoma (GBM) has a dismal prognosis and successful elimination of GBM stem cells (GSCs) is a high-priority as these cells are responsible for tumor regrowth following therapy and ultimately patient relapse. Natural products and their derivatives continue to be a source for the development of e...

Full description

Bibliographic Details
Main Authors: Lorenzo Sansalone, Eduardo A. Veliz, Nadia G. Myrthil, Vasileios Stathias, Winston Walters, Ingrid I. Torrens, Stephan C. Schürer, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
cancer stem cell
endoplasmic reticulum stress
glioblastoma multiforme
unfolded protein response
curcumin
bis-chalcones
brain tumor
glioblastoma stem cell
Online Access:http://www.mdpi.com/2072-6694/11/3/357

Internet

http://www.mdpi.com/2072-6694/11/3/357

Similar Items