Gene- or region-based association study via kernel principal component analysis

<p>Abstract</p> <p>Background</p> <p>In genetic association study, especially in GWAS, gene- or region-based methods have been more popular to detect the association between multiple SNPs and diseases (or traits). Kernel principal component analysis combined with logist...

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Bibliographic Details
Main Authors: Zhao Jinghua, Yuan Zhongshang, He Yungang, Gao Qingsong, Zhang Bingbing, Xue Fuzhong
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/12/75