DNA damage repair protein PARP1 poly (ADP-ribosyl) ates mitotic protein BUB3 regulates mitosis in HeLa cells

Objective To investigate the role and molecular mechanism of poly (ADP-ribose) polymerase 1 (PARP1) in mitosis of HeLa cells. Methods Flow cytometry, immunofluorescent assay and live cell imaging were used to detect the effect of PARP1 on mitosis of HeLa cells. Chromosome karyotype analysis and immu...

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Bibliographic Details
Main Authors: YANG Xue, XU Bo
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-08-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/html/202305002.htm