Impact of the Amyotrophic Lateral Sclerosis Disease on the Biomechanical Properties and Oxidative Stress Metabolism of the Lung Tissue Correlated With the Human Mutant SOD1G93A Protein Accumulation

Impact of the Amyotrophic Lateral Sclerosis Disease on the Biomechanical Properties and Oxidative Stress Metabolism of the Lung Tissue Correlated With the Human Mutant SOD1G93A Protein Accumulation

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease, and ALS incidence is increasing worldwide. Patients with ALS have respiratory failure at the disease’s end stages, leading to death; thus, the lung is one of the most affected organs during disease progression. Tissue stiff...

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Bibliographic Details
Main Authors: Duygu Aydemir, Anjum Naeem Malik, Ibrahim Kulac, Ayse Nazli Basak, Ismail Lazoglu, Nuriye Nuray Ulusu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
ALS
biomechanical test
stiffness
oxidative stress
SOD1
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.810243/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.810243/full

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