A Profile Hidden Markov Model to investigate the distribution and frequency of LanB-encoding lantibiotic modification genes in the human oral and gut microbiome

Background The human microbiota plays a key role in health and disease, and bacteriocins, which are small, bacterially produced, antimicrobial peptides, are likely to have an important function in the stability and dynamics of this community. Here we examined the density and distribution of the subc...

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Bibliographic Details
Main Authors: Calum J. Walsh, Caitriona M. Guinane, Paul W. O’ Toole, Paul D. Cotter
Format: Article
Language:English
Published: PeerJ Inc. 2017-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3254.pdf