Marine Fungi as Producers of Benzocoumarins, a New Class of Inhibitors of Glycogen-Synthase-Kinase 3β

Marine Fungi as Producers of Benzocoumarins, a New Class of Inhibitors of Glycogen-Synthase-Kinase 3β

The glycogen-synthase-kinase 3 (GSK-3) is an important target in drug discovery. This enzyme is involved in the signaling pathways of type 2 diabetes, neurological disorders, cancer, and other diseases. Therefore, inhibitors of GSK-3 are promising drug candidates for the treatment of a broad range o...

Full description

Bibliographic Details
Main Authors: Jutta Wiese, Johannes F. Imhoff, Tobias A. M. Gulder, Antje Labes, Rolf Schmaljohann
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Marine Drugs
Subjects:
GSK-3β
pannorin
alternariol
alternariol-9-methyl ether
Aspergillus
Botrytinia
deep-sea
Online Access:http://www.mdpi.com/1660-3397/14/11/200

Internet

http://www.mdpi.com/1660-3397/14/11/200

Similar Items