Proteomic Identification and Time-Course Monitoring of Secreted Proteins During Expansion of Human Mesenchymal Stem/Stromal in Stirred-Tank Bioreactor

Proteomic Identification and Time-Course Monitoring of Secreted Proteins During Expansion of Human Mesenchymal Stem/Stromal in Stirred-Tank Bioreactor

The therapeutic potential of mesenchymal stem/stromal cells (MSC) is widely recognized for the treatment of several diseases, including acute graft-vs.-host disease (GVHD), hematological malignancies, cardiovascular, bone, and cartilage diseases. More recently, this therapeutic efficacy has been att...

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Bibliographic Details
Main Authors: Amanda Mizukami, Carolina Hassibe Thomé, Germano Aguiar Ferreira, Guilherme Pauperio Lanfredi, Dimas Tadeu Covas, Sharon J. Pitteri, Kamilla Swiech, Vitor Marcel Faça
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stem/stromal cells
umbilical cord matrix
secretome
bioreactors
proteomic analysis
mass spectrometry
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00154/full

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https://www.frontiersin.org/article/10.3389/fbioe.2019.00154/full

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