Dexamethasone inhibits IL-8 via glycolysis and mitochondria-related pathway to regulate inflammatory pain

Dexamethasone inhibits IL-8 via glycolysis and mitochondria-related pathway to regulate inflammatory pain

Abstract Background Dexamethasone (Dexa) has been recently found to exert an analgesic effect, whose action is closely related to IL-8. However, whether dexamethasone induces antinociception via glycolysis and mitochondria-related pathways is still unclear. Methods Right hind paw inflammatory pain i...

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Bibliographic Details
Main Authors: Ren He, Xiaohan Li, Silun Zhang, Yuqiang Liu, Qingsheng Xue, Yan Luo, Buwei Yu, Xiongjuan Li, Zhiheng Liu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Anesthesiology
Subjects:
Dexamethasone
Mitochondrial pathway
Glycolysis
IL-8
Inflammatory pain
Online Access:https://doi.org/10.1186/s12871-023-02277-9

Internet

https://doi.org/10.1186/s12871-023-02277-9

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