Behavioral features and disorganization of oscillatory activity in C57BL/6J mice after acute low dose MK-801 administration

Low dose acute administration of N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 is widely used to model cognition impairments associated with schizophrenia (CIAS) in rodents. However, due to no unified standards for animal strain, dose, route of drug delivery, and the duration of administra...

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Bibliographic Details
Main Authors: Keke Cui, Zhipeng Yu, Le Xu, Wangcong Jiang, Luwan Wang, Xiangqun Wang, Dandan Zou, Jiajie Gu, Feng Gao, Xiaoqing Zhang, Zhengchun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.1001869/full