Structured Illumination Microscopy Improves Spot Detection Performance in Spatial Transcriptomics

Structured Illumination Microscopy Improves Spot Detection Performance in Spatial Transcriptomics

Spatial biology is a rapidly growing research field that focuses on the transcriptomic or proteomic profiling of single cells within tissues with preserved spatial information. Imaging-based spatial transcriptomics uses epifluorescence microscopy, which has shown remarkable results for the identific...

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Bibliographic Details
Main Authors: Alejandro Linares, Carlo Brighi, Sergio Espinola, Francesco Bacchi, Álvaro H. Crevenna
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
structured illumination
spatial transcriptomics
super-resolution
gene expression
in situ sequencing
deconvolution microscopy
Online Access:https://www.mdpi.com/2073-4409/12/9/1310

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https://www.mdpi.com/2073-4409/12/9/1310

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