Pseudotemporal ordering of spatial lymphoid tissue microenvironment profiles trails Unclassified DLBCL at the periphery of the follicle

Pseudotemporal ordering of spatial lymphoid tissue microenvironment profiles trails Unclassified DLBCL at the periphery of the follicle

We have established a pseudotemporal ordering for the transcriptional signatures of distinct microregions within reactive lymphoid tissues, namely germinal center dark zones (DZ), germinal center light zones (LZ), and peri-follicular areas (Peri). By utilizing this pseudotime trajectory derived from...

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Bibliographic Details
Main Authors: Claudio Tripodo, Giorgio Bertolazzi, Valeria Cancila, Gaia Morello, Emilio Iannitto
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
digital spatial profiling
lymphoid tissue microenvironment
pseudotemporal ordering
diffuse large B cell lymphoma
cell-of-origin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1207959/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1207959/full

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