Covalent organic framework based cytoprotective therapy after ischemic stroke

Covalent organic framework based cytoprotective therapy after ischemic stroke

Cytoprotection has emerged as an effective therapeutic strategy for mitigating brain injury following acute ischemic stroke (AIS). The sulfonylurea receptor 1-transient receptor potential M4 (SUR1-TRPM4) channel plays a pivotal role in brain edema and neuroinflammation. However, the practical use of...

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Bibliographic Details
Main Authors: Yuqin Peng, Qingfan Ren, Huanrong Ma, Chuman Lin, Mingjia Yu, Yongchuan Li, Jiancong Chen, Haihao Xu, Peng Zhao, Suyue Pan, Jia Tao, Kaibin Huang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Redox Biology
Subjects:
Covalent organic framework
Cytoprotective therapy
Ischemic stroke
Glyburide
Sulfonylurea receptor 1-transient receptor potential M4
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172400082X

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http://www.sciencedirect.com/science/article/pii/S221323172400082X

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