Mild traumatic brain injury with social defeat stress alters anxiety, contextual fear extinction, and limbic monoamines in adult rats

Mild traumatic brain injury with social defeat stress alters anxiety, contextual fear extinction, and limbic monoamines in adult rats

Mild traumatic brain injury (mTBI) produces symptoms similar to those typifying posttraumatic stress disorder (PTSD) in humans. We sought to determine whether a rodent model of stress concurrent with mTBI produces characteristics of PTSD such as impaired contextual fear extinction, while also exami...

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Bibliographic Details
Main Authors: Daniel eDavies, Dawne eOlson, Danielle eMeyer, Jamie eScholl, Michael eWatt, Pasquale eManzerra, Kenneth eRenner, Gina L Forster
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Anxiety
Fear conditioning
posttraumatic stress disorder
social stress
mild traumatic brain injury
monoamine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00071/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00071/full

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