Oxidation of Methionine 77 in Calmodulin Alters Mouse Growth and Behavior

Oxidation of Methionine 77 in Calmodulin Alters Mouse Growth and Behavior

Methionine 77 in calmodulin can be stereospecifically oxidized to methionine sulfoxide by mammalian methionine sulfoxide reductase A. Whether this has in vivo significance is unknown. We therefore created a mutant mouse in which wild type calmodulin-1 was replaced by a calmodulin containing a mimic...

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Bibliographic Details
Main Authors: Méry Marimoutou, Danielle A. Springer, Chengyu Liu, Geumsoo Kim, Rodney L. Levine
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Antioxidants
Subjects:
calmodulin
methionine sulfoxide reductase A
methionine sulfoxide
methionine
reversible covalent modification
Online Access:http://www.mdpi.com/2076-3921/7/10/140

Internet

http://www.mdpi.com/2076-3921/7/10/140

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