Short-term in vivo testing to discriminate genotoxic carcinogens from non-genotoxic carcinogens and non-carcinogens using next-generation RNA sequencing, DNA microarray, and qPCR

Short-term in vivo testing to discriminate genotoxic carcinogens from non-genotoxic carcinogens and non-carcinogens using next-generation RNA sequencing, DNA microarray, and qPCR

Abstract Next-generation RNA sequencing (RNA-Seq) has identified more differentially expressed protein-coding genes (DEGs) and provided a wider quantitative range of expression level changes than conventional DNA microarrays. JEMS·MMS·Toxicogenomics group studied DEGs with targeted RNA-Seq on freshl...

Full description

Bibliographic Details
Main Authors: Chie Furihata, Takayoshi Suzuki
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Genes and Environment
Subjects:
RNA-Seq
DNA microarray
qPCR
Rodent short-term in vivo test
Genotoxic carcinogen
Non-genotoxic carcinogen
Online Access:https://doi.org/10.1186/s41021-023-00262-9

Internet

https://doi.org/10.1186/s41021-023-00262-9

Similar Items