The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases

Summary: Primary and secondary cone photoreceptor death in retinal degenerative diseases, including age-related macular degeneration (AMD) and retinitis pigmentosa (RP), leads to severe visual impairment and blindness. Although the cone photoreceptor protection in retinal degenerative diseases is cr...

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Bibliographic Details
Main Authors: Leah Rie Varner, Taro Chaya, Yamato Maeda, Ryotaro Tsutsumi, Shanshan Zhou, Toshinori Tsujii, Daisuke Okuzaki, Takahisa Furukawa
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224006011