Abatacept induced granulomatous hepatitis with a sarcoidosis- like reaction: a blinded trial in mice

Abstract Background Abatacept is increasingly used for rheumatoid arthritis (RA) and juvenile idiophathic arthritis (JIA) treatment. However little is known about the risk of hepatotoxicity. The aim of this study was to determine whether the inhibition of the T cell CD28 receptor by abatacept result...

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Bibliographic Details
Main Author: Sultan M. Almogairen
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40360-019-0303-0