Activation of TRPV4 Induces Exocytosis and Ferroptosis in Human Melanoma Cells

Activation of TRPV4 Induces Exocytosis and Ferroptosis in Human Melanoma Cells

TRPV4 (transient receptor potential vanilloid 4), a calcium permeable TRP ion channel, is known to play a key role in endocytosis. However, whether it contributes to exocytosis remains unclear. Here, we report that activation of TRPV4 induced massive exocytosis in both melanoma A375 cell and heterol...

Full description

Bibliographic Details
Main Authors: Mei Li, Jiaojiao Zheng, Tian Wu, Yulin He, Jing Guo, Jiao Xu, Chuanzhou Gao, Shuxian Qu, Qianyi Zhang, Jiayu Zhao, Wei Cheng
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
TRPV4 ion channel
exocytosis
A375 cell
Ca<sup>2+</sup> signaling
ferroptosis
Online Access:https://www.mdpi.com/1422-0067/23/8/4146

Internet

https://www.mdpi.com/1422-0067/23/8/4146

Similar Items