UBE2S and UBE2C confer a poor prognosis to breast cancer via downregulation of Numb

PurposeUbiquitin-conjugating enzymes E2S (UBE2S) and E2C (UBE2C), which mediate the biological process of ubiquitination, have been widely reported in various cancers. Numb, the cell fate determinant and tumor suppressor, was also involved in ubiquitination and proteasomal degradation. However, the...

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Bibliographic Details
Main Authors: Yanjing Guo, Xinyu Chen, Xiaowei Zhang, Xichun Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.992233/full