Thiazolidinediones promote axonal growth through the activation of the JNK pathway.

The axon is a neuronal process involved in protein transport, synaptic plasticity, and neural regeneration. It has been suggested that their structure and function are profoundly impaired in neurodegenerative diseases. Previous evidence suggest that Peroxisome Proliferator-Activated Receptors-γ (PPA...

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Bibliographic Details
Main Authors: Rodrigo A Quintanilla, Juan A Godoy, Ivan Alfaro, Deny Cabezas, Rommy von Bernhardi, Miguel Bronfman, Nibaldo C Inestrosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669289?pdf=render