Effect of moxifloxacin administration on pharmacokinetics of tolfenamic acid in rats

Pharmacokinetics of tolfenamic acid as a single drug (4 mg/kg, intramuscularly) and its co-administration with moxifloxacin (5 mg/kg, intramuscularly) in wistar rats were studied. The plasma drug concentration of tolfenamic acid was assayed by LC-MS/MS. Following intramuscular administration of tolf...

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Main Authors: Satish D. Patel, Kamlesh A. Sadariya, Anil K. Gothi, Urvesh D. Patel, Pradhuman A. Gohil, Mukul R. Jain, Shailesh K. Bhavsar, Aswin M. Thaker
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2011-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000400013