The Effect of SIRT3/Ac-SOD2 Mediated Oxidative Stress and HCN1 Channel Activity on Anesthesia/Surgery Induced Anxiety-Like Behavior in Mice

The Effect of SIRT3/Ac-SOD2 Mediated Oxidative Stress and HCN1 Channel Activity on Anesthesia/Surgery Induced Anxiety-Like Behavior in Mice

Anxiety disorders are the most common psychiatric diseases, and perioperative factors often increase the incidence of anxiety. However, the mechanism and treatment for perioperative anxiety, especially anesthesia/surgery-induced postoperative anxiety, are largely unknown. Sirtuin 3 (SIRT3) which loc...

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Bibliographic Details
Main Authors: Hui-Hui Miao, Qiang Liu, Ning Wang, Yan-Ping Liu, Chen Chen, Hai-Bi Wang, Hui Huang, Wei-Feng Wu, Jia-Tao Lin, Yong-Kang Qiu, Chuan-Wu Zhang, Cheng-Hua Zhou, Yu-Qing Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Medicine
Subjects:
anxiety
anesthesia/surgery
SIRT3
SOD2
HCN1
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.783931/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.783931/full

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