Molecular docking and synthesis of N-alkyl-isatin-3-imino aromatic amine derivatives and their antileishmanial and cytotoxic activities

Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties. N-substituted isatins were reported to show cytotoxic activi...

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Bibliographic Details
Main Authors: Farshid Hassanzadeh, Seyed Hossein Hejazi, Elham Jafari, Atefeh Mohammadi fard, Hojjat Sadeghi-aliabadi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2024;volume=19;issue=2;spage=238;epage=250;aulast=Hassanzadeh