MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-κB signaling

MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-κB signaling

Abstract Background Histone modification plays essential roles in hepatocellular carcinoma (HCC) pathogenesis, but the regulatory mechanisms remain poorly understood. In this study, we aimed to analyze the roles of Megakaryoblastic leukemia 1 (MKL1) and its regulation of COMPASS (complex of proteins...

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Bibliographic Details
Main Authors: Zhao Liu, Jiuzheng Sun, Chuanzhi Li, Liyou Xu, Jun Liu
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Cancer
Subjects:
Ash2
Hepatocellular carcinoma
MKL1
p65
Wdr5
Online Access:https://doi.org/10.1186/s12885-021-08185-w

Internet

https://doi.org/10.1186/s12885-021-08185-w

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