Deep Modeling of Regulating Effects of Small Molecules on Longevity-Associated Genes

Deep Modeling of Regulating Effects of Small Molecules on Longevity-Associated Genes

Aging is considered an inevitable process that causes deleterious effects in the functioning and appearance of cells, tissues, and organs. Recent emergence of large-scale gene expression datasets and significant advances in machine learning techniques have enabled drug repurposing efforts in promoti...

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Bibliographic Details
Main Authors: Jiaying You, Michael Hsing, Artem Cherkasov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
library of integrated network-based cellular signatures (LINCS)
longevity
gene regulating effects
gene descriptors
molecular fingerprints
machine learning
Online Access:https://www.mdpi.com/1424-8247/14/10/948

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https://www.mdpi.com/1424-8247/14/10/948

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