Astrocyte focal adhesion kinase reduces passive stress coping by inhibiting ciliary neurotrophic factor only in female mice

Astrocyte focal adhesion kinase reduces passive stress coping by inhibiting ciliary neurotrophic factor only in female mice

Astrocytes have been implicated in stress responses and produce ciliary neurotrophic factor (CNTF), which we have shown in the mouse medial amygdala (MeA) to promote passive stress coping response only in females. Pharmacological inhibition of focal adhesion kinase (FAK) upregulates CNTF expression....

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Bibliographic Details
Main Authors: Cuihong Jia, W. Drew Gill, Chiharu Lovins, Russell W. Brown, Theo Hagg
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Neurobiology of Stress
Subjects:
Chronic unpredictable stress
FAK inhibitor
Passive stress coping
Progesterone
Sex dimorphism
Stress-related disorders
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289524000171

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http://www.sciencedirect.com/science/article/pii/S2352289524000171

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