FBXW7 alleviates hyperglycemia-induced endothelial oxidative stress injury via ROS and PARP inhibition

FBXW7 alleviates hyperglycemia-induced endothelial oxidative stress injury via ROS and PARP inhibition

Diabetic retinopathy (DR) and other diabetic vascular complications are the leading cause of death and disability in patients with suboptimum glycemic control. In the pathogenesis of diabetic vascular diseases, hyperglycemia-induced oxidative stress, DNA damage, and poly-ADP-ribose-polymerase (PARP)...

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Bibliographic Details
Main Authors: Shenping Li, Junjie Deng, Dandan Sun, Shimei Chen, Xieyi Yao, Ning Wang, Jian Zhang, Qing Gu, Shuchang Zhang, Jing Wang, Shaopin Zhu, Hong Zhu, Huiming Li, Xun Xu, Fang Wei
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Redox Biology
Subjects:
Diabetic retinopathy
DNA damage
Endothelial cell
Mitochondria
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722003020

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http://www.sciencedirect.com/science/article/pii/S2213231722003020

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