KIF15 is essential for USP10-mediated PGK1 deubiquitination during the glycolysis of pancreatic cancer
Abstract Glycolysis is the most predominant metabolic reprogramming of pancreatic cancer (PC), the underlying mechanism of which in PC cells remains unclear. In this study, we found for the first time that KIF15 promotes the glycolytic capacity of PC cells and PC tumor growth. Moreover, the expressi...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-02-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05679-2 |