Persisting viral sequences shape microbial CRISPR-based immunity.

Persisting viral sequences shape microbial CRISPR-based immunity.

Well-studied innate immune systems exist throughout bacteria and archaea, but a more recently discovered genomic locus may offer prokaryotes surprising immunological adaptability. Mediated by a cassette-like genomic locus termed Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), the...

Full description

Bibliographic Details
Main Authors: Ariel D Weinberger, Christine L Sun, Mateusz M Pluciński, Vincent J Denef, Brian C Thomas, Philippe Horvath, Rodolphe Barrangou, Michael S Gilmore, Wayne M Getz, Jillian F Banfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3330103?pdf=render

Internet

http://europepmc.org/articles/PMC3330103?pdf=render

Similar Items