Does structurally-mature dengue virion matter in vaccine preparation in post-Dengvaxia era?

The unexpectedly low vaccine efficacy of Dengvaxia®, developed by Sanofi Pasteur, and a higher risk of severe diseases after vaccination among dengue-naive children or children younger than 6 years old, have cast skepticism about the safety of dengue vaccination resulting in the suspension of school...

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Bibliographic Details
Main Authors: Jedhan Ucat Galula, Gielenny M. Salem, Gwong-Jen J. Chang, Day-Yu Chao
Format: Article
Language:English
Published: Taylor & Francis Group 2019-10-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2019.1643676