Tumor Growth Remains Refractory to <i>Myc</i> Ablation in Host Macrophages

Tumor Growth Remains Refractory to <i>Myc</i> Ablation in Host Macrophages

Aberrant expression of the oncoprotein c-Myc (Myc) is frequently observed in solid tumors and is associated with reduced overall survival. In addition to well-recognized cancer cell-intrinsic roles of Myc, studies have also suggested tumor-promoting roles for Myc in cells of the tumor microenvironme...

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Bibliographic Details
Main Authors: Riley J. Morrow, Amr H. Allam, Josh Konecnik, David Baloyan, Christine Dijkstra, Moritz F. Eissmann, Saumya P. Jacob, Megan O’Brien, Ashleigh R. Poh, Matthias Ernst
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
Myc
gastrointestinal cancer
myeloid cells
macrophages
Online Access:https://www.mdpi.com/2073-4409/11/24/4104

Internet

https://www.mdpi.com/2073-4409/11/24/4104

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