DncV Synthesizes Cyclic GMP-AMP and Regulates Biofilm Formation and Motility in <italic toggle="yes">Escherichia coli</italic> ECOR31

ABSTRACT Cyclic dinucleotides (cDNs) act as intracellular second messengers, modulating bacterial physiology to regulate the fundamental life style transition between motility and sessility commonly known as biofilm formation. Cyclic GMP-AMP (cGAMP), synthesized by the dinucleotide cyclase DncV, is...

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Bibliographic Details
Main Authors: Fengyang Li, Annika Cimdins, Manfred Rohde, Lothar Jänsch, Volkhard Kaever, Manfred Nimtz, Ute Römling
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02492-18