Investigating the Synergistic Effect of Palmitoylethanolamide and Ganaxolone in PTZ-induced Tonic-clonic Seizures

Background and Aim: Anticonvulsive effects of neurosteroids were shown in animal models. Endocannabinoids modulate neuronal excitability. In this study, we investigated the synergism of the simultaneous application of Palmitoylethanolamide (PEA) as an endocannabinoid and Ganaxolone as a neurosteroid...

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Bibliographic Details
Main Authors: Hesamodin Bagheripoor, Abbas Alimoradian, Mehdi Sadegh
Format: Article
Language:fas
Published: Kurdistan University of Medical Sciences 2023-03-01
Series:مجله علمی دانشگاه علوم پزشکی کردستان
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Online Access:http://sjku.muk.ac.ir/article-1-6998-en.html