High-dimensional deconstruction of ovarian cancer at single-cell precision reveals HEBP2 that reshape the TIME and drive carboplatin resistance

High-dimensional deconstruction of ovarian cancer at single-cell precision reveals HEBP2 that reshape the TIME and drive carboplatin resistance

Background: Single-cell sequencing was employed to analyze the tumor immune microenvironment in ovarian cancer (OC) patients, exploring the evolutionary roles of various macrophage subgroups in OC progression and their correlation with fatty acid metabolism-related genes in contributing to drug resi...

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Bibliographic Details
Main Authors: BiKang Yang, Miao Dai
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Translational Oncology
Subjects:
Single-cell
Ovarian cancer
Drug resistance
HEBP2
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000421

Internet

http://www.sciencedirect.com/science/article/pii/S1936523324000421

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