Development, qualification, validation and application of the Ames test using a VITROCELL® VC10® smoke exposure system

The Ames test has established use in the assessment of potential mutagenicity of tobacco products but has generally been performed using partitioned exposures (e.g. total particulate matter [TPM], gas vapor phase [GVP]) rather than whole smoke (WS). The VITROCELL®VC10® smoke exposure system offers m...

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Bibliographic Details
Main Authors: Kathy Fowler, Wanda Fields, Victoria Hargreaves, Lesley Reeve, Betsy Bombick
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750018302026