The shaky foundations of simulating single-cell RNA sequencing data

The shaky foundations of simulating single-cell RNA sequencing data

Abstract Background With the emergence of hundreds of single-cell RNA-sequencing (scRNA-seq) datasets, the number of computational tools to analyze aspects of the generated data has grown rapidly. As a result, there is a recurring need to demonstrate whether newly developed methods are truly perform...

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Bibliographic Details
Main Authors: Helena L. Crowell, Sarah X. Morillo Leonardo, Charlotte Soneson, Mark D. Robinson
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Genome Biology
Subjects:
Benchmarking
Simulation
Single-cell RNA-seq
Online Access:https://doi.org/10.1186/s13059-023-02904-1

Internet

https://doi.org/10.1186/s13059-023-02904-1

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