Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations

Abstract Identifying patients that are likely to respond to cancer immunotherapy is an important, yet highly challenging clinical need. Using 3139 patients across 17 different cancer types, we comprehensively studied the ability of two common copy-number alteration (CNA) scores—the tumor aneuploidy...

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Bibliographic Details
Main Authors: Tian-Gen Chang, Yingying Cao, Eldad D. Shulman, Uri Ben-David, Alejandro A. Schäffer, Eytan Ruppin
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00408-6