Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations
Abstract Identifying patients that are likely to respond to cancer immunotherapy is an important, yet highly challenging clinical need. Using 3139 patients across 17 different cancer types, we comprehensively studied the ability of two common copy-number alteration (CNA) scores—the tumor aneuploidy...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
|
Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-023-00408-6 |