Sclerostin Antibody Mitigates Estrogen Deficiency-Inducted Marrow Lipid Accumulation Assessed by Proton MR Spectroscopy

Sclerostin Antibody Mitigates Estrogen Deficiency-Inducted Marrow Lipid Accumulation Assessed by Proton MR Spectroscopy

Sclerostin knock-out mice or sclerostin antibody (Scl-Ab) treated wild-type mice displayed decreased marrow adiposity. But the effects of Scl-Ab on estrogen deficiency-induced marrow fat expansion remain elusive. In this work, 45 female New Zealand rabbits were equally divided into sham-operation, o...

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Bibliographic Details
Main Authors: Shaojun Li, Bingcang Huang, Bo Jiang, Mingjun Gu, Xiaodan Yang, Ying Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Endocrinology
Subjects:
sclerostin
bone marrow
osteoporosis
estrogen deficiency
MR spectroscopy
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00159/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00159/full

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